Immunohistochemistry Kits and Reagents
ABclonal Technology Phospho-p38 MAPK-T180/Y182 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Biolegend LEGENDplex™ Hu Type 1/2/3 Interferon Panel (5-plex) w/ VbP V02; Reactivity: Human; Apps: Multiplex - Panel; Size: 100 tests
LEGENDplex™ Hu Type 1/2/3 Interferon Panel (5-plex) w/ VbP V02; Reactivity: Human; Apps: Multiplex - Panel; Size: 100 tests
ABclonal Technology 488 Conjugated AIF1/IBA1
Enables actin filament binding activity and calcium ion binding activity Involved in several processes including Rac protein signal transduction actin filament organization and ruffle assembly Acts upstream of or within actin filament bundle assembly Located in several cellular components including actin filament phagocytic cup and ruffle membrane Is expressed in adrenal cortex central nervous system embryo mesenchyme and retina Human ortholog(s) of this gene implicated in type 1 diabetes mellitus Orthologous to human AIF1 (allograft inflammatory factor 1)
ABclonal Technology Phospho-p38 MAPK-Y182 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Surmodics Inc 650 nm Liquid Stop Solution for TMB Microwell Substrates, 100mL
A liquid stop solution used in end point ELISA applications where a TMB substrate is used as the detection mechanism. Absorbance is read in the blue spectral range (650 nm).
Medchemexpress LLC Discoidin domain receptor 1 (DDR1), rat recombinant protein (HEK293, His-tag) | >95.0% | 500 UG
Recombinant rat discoidin domain receptor 1 (DDR1) expressed in HEK293 cells with a C-terminal His tag. This purified protein is designed for biochemical and cell-based studies of collagen-mediated signaling, matrix remodeling, and protein-protein interactions. Purity is reported as greater than 95% by reducing SDS-PAGE, and multiple size formats are available, including a 500 μg option.
- HEK293-expressed rat DDR1 with C-terminal His tag.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Available in multiple sizes, including a 500 μg format.
- Suitable for biochemical and cell-based assays.
- Useful for studying collagen-mediated signaling, matrix remodeling, and receptor interactions.
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Phospho-DAP12 (Tyr91 & total) Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Multiplex Phospho-DAP12 (Tyr91 & total) Detection Kit, 500 Assay Points
ABclonal Technology ALKBH5 Rabbit mAb
Enables mRNA N6-methyladenosine dioxygenase activity Involved in RNA metabolic process mRNA export from nucleus and response to hypoxia Located in Golgi apparatus cytosol and nuclear speck ALKBH5 also named as ABH5 and OFOXD1 is a Dioxygenase that demethylates RNA by oxidative demethylation It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo ALKBH5 is required for spermatogenesis
ABclonal Technology Phospho-PDK1/PDPK1-S241 Rabbit pAb
Enables 3-phosphoinositide-dependent protein kinase activity, phospholipase activator activity, and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway, regulation of protein kinase activity, and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection, cytosol, and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
Leica Biosystems LEICA EPITPE RETRVL SOLN PH61L
Novocastra Epitope Retrieval Solutions are intended for Heat Induced Epitope Retrieval (HIER) on formalin-fixed, paraffin-embedded tissue sections as part of an immunohistochemical procedure. HIER using an appropriate pH solution improves the staining of some antibodies by exposing epitopes within tissue that have been masked during fixation. A universal HIER technique suitable for all epitopes does not exist. A combination of different heating methods and epitope retrieval solutions may be used to optimize unmasking of antigens where this technique is recommended. HIER is not recommended for all antibodies. Optimum conditions for epitope retrieval should be validated by the user, as these are dependent upon tissue, fixation and/or primary antibody. RE7119 is supplied as a 1 L volume, sufficient to prepare 10 L of working solution. It is a Tris/EDTA-based buffer and should be diluted with de-ionized water to prepare a working solution. For in vitro diagnostic use.
Cell Signaling Technology FoxP3/Transcription Factor Fixation/Permeabilization Diluent (1X) 160 ml
FoxP3/Transcription Factor Fixation/Permeabilization Diluent (1X) 160 ml
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & DAB/Ni), 6ML
Abcam's TripleStain IHC Kit (ab183291) is designed to be used with user-supplied goat, mouse and rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology δ-Catenin/p120 Catenin Rabbit pAb
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.
Cayman Chemical p38 MAPK InhIbItr IV 5mg
An ATP-competitive inhibitor of p38 MAPKs; inhibits p38α, p38β, p38��, and p38δ MAPKs (IC50s = 0.13, 0.55, 5.47, and 8.63 μM, respectively); inhibits LPS-induced TNF-α and IL-1β cytokine production in human peripheral blood mononuclear cells (IC50s = 22 and 44 nM, respectively)